Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 5/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773803 | 0.87 | GSK3B (0.44) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8731834 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL2023894 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8735563 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1POLBPIM1HPGD | |
| SCHEMBL9387332 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8733989 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL3720416 | 0.80 | TOP2A (0.58) | KDM4EALDH1A1POLBTOP2ATOP2B | |
| SCHEMBL8733567 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1TOP1PIM1KCNH2 | |
| SCHEMBL9038570 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9094282 | 0.78 | TOP2A (0.44) | KDM4EALDH1A1POLBTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |