Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.31 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735573 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8735563 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8733567 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL8733989 | 0.67 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL14208163 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5164189 | 0.67 | STAT3 (0.32) | STAT3 | |
| SCHEMBL8735576 | 0.66 | PIM1 (0.38) | PIM1 | |
| SCHEMBL8731834 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8503513 | 0.66 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL3869157 | 0.65 | KDM4E (0.42) | STAT3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |