Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528861 | 0.85 | TSHR (0.55) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL671515 | 0.82 | TSHR (0.60) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL27455502 | 0.81 | TSHR (0.55) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL3292782 | 0.81 | TSHR (0.75) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL8956380 | 0.81 | TSHR (0.58) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL7090996 | 0.80 | LOXL2 (0.55) | TSHRLOXL2KCNH2KCNJ1IDO1 | |
| SCHEMBL8507118 | 0.79 | TSHR (0.57) | TSHRACHEALDH1A1CYP2C19POLB | |
| SCHEMBL670267 | 0.78 | TSHR (0.64) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL18913824 | 0.77 | TSHR (0.69) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL30758863 | 0.77 | TSHR (0.69) | TSHRLOXL2KCNH2KCNJ1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1119337-C | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1239955-A | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| CN-1239957-A | Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |