Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237707 | 0.89 | TSHR (0.56) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL15453241 | 0.85 | TSHR (0.53) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL15453242 | 0.85 | TSHR (0.53) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL3292782 | 0.83 | TSHR (0.75) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL8956380 | 0.82 | TSHR (0.58) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL8734120 | 0.82 | TSHR (0.58) | TSHRLOXL2KCNH2KCNJ1HRH3 | |
| SCHEMBL9528716 | 0.81 | LOXL2 (0.59) | TSHRLOXL2KCNH2KCNJ1IDO1 | |
| SCHEMBL483755 | 0.81 | LOXL2 (0.59) | TSHRLOXL2KCNH2KCNJ1IDO1 | |
| SCHEMBL9671868 | 0.80 | HIF1A (0.37) | ALDH1A1CA2 | |
| SCHEMBL22622364 | 0.79 | KCNH2 (0.56) | TSHRLOXL2KCNH2KCNJ1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311567-B | One prepares the method for 4-amino-3-(4-amino-benzene) furo [2,3-d] pyrimidine | SHANGHAI INSTITUTE OF TECHNOLOGY (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-104311567-A | Method for preparing 4-amino-3-(4-aminobenzene)furo[2,3-d] pyrimidine | SHANGHAI INST TECHNOLOGY | 2015-01-28 | — | — | CN | claimed |
| EP-2210900-A2 | Analogues of GLP-1 | IPSEN PHARMA (FR) | 2010-07-28 | — | — | EP | claimed |
| US-7759471-B2 | nucleotide monomer used to make protected RNA that has similar stability to the DNA molecule | AGILENT TECHNOLOGIES, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-2001896-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | Agilent Technologies, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| EP-1711523-A4 | ANALOGUES OF GLP-1 | SOD CONSEILS RECH APPLIC (FR) | 2008-05-21 | — | — | EP | claimed |
| WO-2007112263-A2 | MONOMER COMPOSITIONS FOR THE SYNTHESIS OF RNA, METHODS OF SYNTHESIS, AND METHODS OF DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | WO | claimed |
| US-20070100138-A1 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | THE REGENTS OF THE UNIVERSITY OF COLORADO | 2007-05-03 | — | — | US | claimed |
| US-20070100136-A1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES, INC. | 2007-05-03 | — | — | US | claimed |
| US-20070042952-A1 | Analogues of glp-1 | IPSEN PHARMA S.A.S. (FR) | 2007-02-22 | — | — | US | claimed |
| EP-1711523-A1 | ANALOGUES OF GLP-1 | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2006-10-18 | — | — | EP | claimed |
| WO-2005058955-A1 | ANALOGUES OF GLP-1 | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2005-06-30 | — | — | WO | claimed |
| US-20240217917-A1 | PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS | THE UNIVERSITY OF STAVANGER (NO) | 2024-07-04 | — | — | US | disclosed |
| WO-2024044657-A1 | BIOCATALYSTS AND METHODS THEREOF | TESARO, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-110950781-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2020-04-03 | — | — | CN | disclosed |
| CN-107537481-B | Supported monatomic rhodium-based catalyst and application thereof in olefin hydroformylation reaction | 中国科学院大连化学物理研究所 | 2020-03-31 | — | — | CN | disclosed |
| WO-1992021691-A1 | 2',5'-NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-12-10 | — | — | WO | disclosed |
| US-4424331-A | Stable, anaerobically-hardening adhesives containing mixed amine oxide/HN-acidic compound initiators | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-01-03 | — | — | US | disclosed |
| US-4386194-A | ACRYLIC ESTERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1983-05-31 | — | — | US | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100136-A1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | RNGTT, RNMT, NSUN2 | TSHR 4260/4885LOXL2 2854/4885KCNH2 4669/4885 |
| US-20070042952-A1 | Analogues of glp-1 | GLP1R, IAPP, GIPR | TSHR 117/4885LOXL2 3736/4885KCNH2 2050/4885 |
| US-20240217917-A1 | PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS | DDT, DDC, CTRC | TSHR 2972/4885LOXL2 2047/4885KCNH2 2301/4885 |
| US-20070100138-A1 | Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection | POLN, NT5C3B, PCNA | TSHR 4204/4885LOXL2 4192/4885KCNH2 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.