Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295842 | 0.89 | THRB (0.49) | THRBTSHRALDH1A1GABRPGABRD | |
| SCHEMBL11713496 | 0.85 | TSHR (0.47) | THRBTSHRALDH1A1GABRPGABRD | |
| SCHEMBL4835674 | 0.84 | THRB (0.50) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL496658 | 0.83 | TSHR (0.57) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL41669 | 0.83 | TSHR (0.63) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL65233 | 0.82 | TSHR (0.55) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL10628321 | 0.82 | TSHR (0.55) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL27733083 | 0.82 | TSHR (0.55) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL27642349 | 0.82 | TSHR (0.55) | THRBTSHRALDH1A1TDP1POLB | |
| SCHEMBL5827329 | 0.81 | THRB (0.52) | THRBTSHRALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5444110-A | A triazine compound and a plasticizer | NIPPON ZEON CO., LTD. (JP) | 1995-08-22 | — | — | US | claimed |
| CN-117209418-A | Preparation and purification method of high-purity nicardipine hydrochloride | 华仁医学研究(安徽)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| EP-0611088-B1 | Crosslinkable PVC-plastisol | NIPPON ZEON CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5444110-A | A triazine compound and a plasticizer | NIPPON ZEON CO., LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5350550-A | Method of production of a plastic laminate | NIPPON ZEON CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0611088-A1 | Crosslinkable PVC-plastisol | NIPPON ZEON CO., LTD. (JP) | 1994-08-17 | — | — | EP | disclosed |