SCHEMBL8734173

SCHEMBL8734173

CCC1=Cc2ccccc2C1C1=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9068095 0.77
SCHEMBL6937046 0.76
SCHEMBL28837165 0.76
SCHEMBL8853881 0.70 SLC6A4 (0.41) HTR2A
SCHEMBL5859366 0.68 CYP11B1 (0.33) HTR2AHTR2CHTR2BCYP11B1CYP11B2
SCHEMBL27372929 0.68 CYP11B1 (0.33) HTR2AHTR2CHTR2BCYP11B1CYP11B2
SCHEMBL6344924 0.68 DRD2 (0.38) HTR2AHTR2CHTR2BCYP11B1CYP11B2
SCHEMBL4660518 0.66 HTR2A (0.39) HTR2AHTR2CHTR2BCYP11B1CYP11B2
SCHEMBL7919016 0.66 KDM4E (0.33) HTR2AHTR2CHTR2BCYP11B1CYP11B2
SCHEMBL1452158 0.66 HTR2A (0.39) HTR2AHTR2CHTR2BCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793679-B1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES DOW CHEMICAL CO (US) 1998-11-25 EP disclosed
EP-0793679-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1997-09-10 EP disclosed
WO-1996016095-A1 ETHYLENE HOMOPOLYMERIZATION USING GROUP 3 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1996-05-30 WO disclosed
US-5464906-A Polymerization catalyst THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed