Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089446 | 0.81 | CYP3A4 (0.39) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL8082953 | 0.77 | CYP3A4 (0.36) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL8097016 | 0.76 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL8089722 | 0.74 | CTRC (0.37) | CYP3A4HPGDTSHRHSD17B10MAPK1 | |
| SCHEMBL1004018 | 0.71 | CYP3A4 (0.59) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL8148096 | 0.69 | CYP3A4 (0.47) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL16860554 | 0.65 | CYP3A4 (0.50) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL28675338 | 0.65 | CYP3A4 (0.43) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL5614054 | 0.65 | CYP3A4 (0.43) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 | |
| SCHEMBL22138546 | 0.65 | HSD17B10 (0.59) | CYP3A4HPGDTSHRHSD17B10HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |