SCHEMBL28675338

SCHEMBL28675338

Cc1c(F)cc(Cl)c(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 1/20 0.35
HPGD P15428 4/20 0.35
HSD17B10 Q99714 4/20 0.35
TSHR P16473 3/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPK1 P28482 1/20 0.35
AHR P35869 3/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
CASP1 P29466 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30
AKR1B1 P15121 1/20 0.30
HTR3E A5X5Y0 1/20 0.30
HTR3B O95264 1/20 0.30
HTR3A P46098 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7936911 0.79 CYP3A4 (0.40) CYP3A4ALDH1A1HDAC1HDAC6POLB
SCHEMBL21196047 0.78 HDAC1 (0.32) CYP3A4ALDH1A1HDAC1HDAC6
SCHEMBL18885784 0.76 HDAC1 (0.32) HDAC1HDAC6POLBAPEX1RAPGEF4
SCHEMBL1004018 0.75 CYP3A4 (0.59) CYP3A4ALDH1A1HPGDHSD17B10TSHR
SCHEMBL4557570 0.75 CYP3A4 (0.59) CYP3A4ALDH1A1HPGDHSD17B10TSHR
SCHEMBL16589257 0.74 POLB (0.33) CYP3A4HDAC1HDAC6POLBAPEX1
SCHEMBL22399221 0.74 HDAC1 (0.35) HDAC1HDAC6POLBAPEX1
SCHEMBL5386141 0.74 HDAC1 (0.35) HDAC1HDAC6POLBAPEX1
SCHEMBL1756502 0.72 CYP3A4 (0.47) CYP3A4ALDH1A1HPGDHSD17B10TSHR
SCHEMBL8148096 0.72 CYP3A4 (0.47) CYP3A4ALDH1A1HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861007-B Method for disposing 2-chloro-6 fluorobenzaldehyde distillation residues 浙江大洋生物科技集团股份有限公司 2023-04-25 CN disclosed
CN-113861007-A Method for treating distillation residue of 2-chloro-6-fluorobenzaldehyde 浙江大洋生物科技集团股份有限公司 2021-12-31 CN disclosed