Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074852 | 0.83 | LMNA (0.49) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL2492792 | 0.81 | LMNA (0.47) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL27361301 | 0.80 | LMNA (0.44) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL9343369 | 0.76 | CYP3A4 (0.35) | LMNAKMT2AKDM4EMEN1MAPT | |
| SCHEMBL6648950 | 0.76 | LMNA (0.47) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL6746708 | 0.75 | LMNA (0.40) | LMNATDP1POLBKMT2AKDM4E | |
| SCHEMBL721712 | 0.74 | KMT2A (0.33) | LMNAKMT2ATHRBNPSR1TSHR | |
| SCHEMBL29091067 | 0.74 | LMNA (0.39) | LMNATDP1KMT2AKDM4EMEN1 | |
| SCHEMBL9699425 | 0.73 | KMT2A (0.32) | LMNAKMT2A | |
| SCHEMBL29173948 | 0.73 | LMNA (0.44) | LMNATDP1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685535-B1 | Radiation-curable compositions | UCB SA (BE) | 1998-01-07 | — | — | EP | claimed |