Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358106 | 0.85 | SMN1; SMN2 (0.39) | LMNAMITFSMN1; SMN2POLBMAPT | |
| SCHEMBL2492792 | 0.77 | LMNA (0.47) | LMNASMN1; SMN2TDP1POLBMAPT | |
| SCHEMBL29091067 | 0.76 | LMNA (0.39) | LMNAMITFSMN1; SMN2TDP1MAPT | |
| SCHEMBL8734180 | 0.75 | LMNA (0.45) | LMNATDP1POLBMAPTALDH1A1 | |
| SCHEMBL11276999 | 0.74 | LMNA (0.46) | LMNAMITFSMN1; SMN2POLBMAPT | |
| SCHEMBL8208634 | 0.73 | LMNA (0.50) | LMNATDP1POLBMAPTKDM4E | |
| SCHEMBL14973716 | 0.73 | THRB (0.34) | ALDH1A1KMT2ATHRB | |
| SCHEMBL6648950 | 0.71 | LMNA (0.47) | LMNAMITFSMN1; SMN2TDP1POLB | |
| SCHEMBL28977315 | 0.71 | TSHR (0.49) | LMNASMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL20649345 | 0.70 | LMNA (0.35) | LMNAMITFSMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699544-B2 | Self-reinforced shaped article | ROEHM GMBH & CO. KG (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030017289-A1 | Self-reinforcing thermoplastically-deformable semi-finished product, in particular for the production of sanitary items, method for production thereof and moulded bodies made therefrom | ROEHM GMBH & CO. KG (DE) | 2003-01-23 | — | — | US | disclosed |