Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736537 | 0.81 | CYSLTR1 (0.82) | CYSLTR1GPBAR1 | |
| SCHEMBL8734145 | 0.81 | CYSLTR1 (1.00) | CYSLTR1GPBAR1 | |
| SCHEMBL7801642 | 0.81 | GPBAR1 (0.81) | CYSLTR1GPBAR1 | |
| SCHEMBL7801672 | 0.81 | GPBAR1 (0.85) | CYSLTR1GPBAR1PDE10A | |
| SCHEMBL421067 | 0.81 | GPBAR1 (1.00) | CYSLTR1GPBAR1PDE10A | |
| SCHEMBL9581634 | 0.79 | GPBAR1 (0.97) | CYSLTR1GPBAR1PDE10A | |
| SCHEMBL9581618 | 0.79 | GPBAR1 (0.97) | CYSLTR1GPBAR1PDE10A | |
| SCHEMBL8735687 | 0.77 | GPBAR1 (0.74) | CYSLTR1GPBAR1 | |
| SCHEMBL26632676 | 0.77 | GPBAR1 (0.92) | CYSLTR1GPBAR1PDE10A | |
| SCHEMBL9335358 | 0.77 | GPBAR1 (0.60) | CYSLTR1GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |