⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907695 | 0.72 | — | — | |
| SCHEMBL28057193 | 0.68 | — | — | |
| SCHEMBL28428882 | 0.61 | — | — | |
| SCHEMBL7610154 | 0.60 | — | — | |
| SCHEMBL8960854 | 0.60 | — | — | |
| SCHEMBL28009083 | 0.58 | TSHR (0.32) | — | |
| SCHEMBL3856006 | 0.56 | — | — | |
| SCHEMBL20893625 | 0.56 | ACHE (0.38) | — | |
| SCHEMBL8402516 | 0.56 | THRB (0.32) | — | |
| SCHEMBL6938850 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494842-B1 | Rigid contact lenses with improved oxygen permeability | CIBA GEIGY AG (CH) | 1998-04-22 | — | — | EP | claimed |
| EP-0401990-B1 | Prepolymers useful in biomedical devices | BAUSCH & LOMB (US) | 1995-08-02 | — | — | EP | claimed |
| CN-109070503-B | Colored contact lenses and methods of making same | 望隼科技股份有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-112213868-A | Functional contact lens and method for dyeing functional contact lens | 望隼科技股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-105440226-A | Silicon-containing hydrogel contact lens and manufacturing method of silicon-containing hydrogel | WANGSUN TECH CO LTD | 2016-03-30 | — | — | CN | disclosed |