SCHEMBL8734645

SCHEMBL8734645

Cc1cccc(Cl)c1S(=O)(=O)OCP(C)(=O)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.32
SLC40A1 Q9NP59 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MCOLN3 Q8TDD5 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732325 0.92 TSHR (0.34) NR3C1SMN1; SMN2TSHRLMNAPOLB
SCHEMBL8732446 0.88 NR3C1 (0.35) NR3C1SMN1; SMN2SLC40A1TSHRMEN1
SCHEMBL8762814 0.88 NR3C1 (0.34) NR3C1SLC40A1
SCHEMBL8652680 0.86 NR3C1 (0.34) NR3C1SMN1; SMN2SLC40A1TSHRMEN1
SCHEMBL8734851 0.86 TSHR (0.32) SMN1; SMN2TSHRL3MBTL1
SCHEMBL8732334 0.85 NR3C1 (0.34) NR3C1SMN1; SMN2SLC40A1TSHR
SCHEMBL8734903 0.83 SLC40A1 (0.33) NR3C1SLC40A1MEN1LMNAHTT
SCHEMBL8731903 0.83 NR3C1 (0.33) NR3C1SMN1; SMN2SLC40A1TSHRMEN1
SCHEMBL8734800 0.82 MAPT (0.30) LMNAL3MBTL1
SCHEMBL8729940 0.82 TSHR (0.32) SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed