SCHEMBL8734663

SCHEMBL8734663

C=C(C)C(=O)NC(N(C)C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.41
RXFP1 Q9HBX9 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28135393 0.74 TGFBR1 (0.44) TGFBR1RXFP1ALDH1A1
SCHEMBL491239 0.74 TGFBR1 (0.44) TGFBR1RXFP1ALDH1A1
SCHEMBL27628846 0.74 TGFBR1 (0.44) TGFBR1RXFP1ALDH1A1
SCHEMBL25873450 0.74 TGFBR1 (0.44) TGFBR1RXFP1ALDH1A1
SCHEMBL7757007 0.74 TGFBR1 (0.44) TGFBR1RXFP1ALDH1A1
SCHEMBL9730259 0.71 CHRNB2 (0.32) ALDH1A1
SCHEMBL9134755 0.71 TSHR (0.50) ALDH1A1
SCHEMBL21342532 0.71 TGFBR1 (0.50) TGFBR1RXFP1ALDH1A1
SCHEMBL21597052 0.69 TGFBR1 (0.44) TGFBR1RXFP1
SCHEMBL3947300 0.69 TGFBR1 (0.40) TGFBR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278267-B1 RETANNING PROCESS Chemische Fabrik Stockhausen GmbH (DE) 1991-08-07 EP claimed
US-4980437-A OF LEATHER; COPOLYMER OF ACRYLIC ACID OR METHACRYLIC ACID AND N-ALKYL ACRLYLAMIDES OR METHACRYLAMIDES; IMPROVED ORGANOLEPTIC PROPERTIES, SMOOTHNESS, LUSTER CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1990-12-25 US claimed
US-4813968-A Retanning process CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1989-03-21 US claimed
EP-0256312-A2 Amphoteric hydrosoluble polymers, process for their preparation and their use as auxiliary dispersing agents Chemische Fabrik Stockhausen GmbH (DE) 1988-02-24 EP claimed
EP-0868459-A1 COATING AGENT AND METHOD OF COATING, IN PARTICULAR FOR USE ON PLASTIC SUBSTRATES Herberts Gesellschaft mit beschränkter Haftung (DE) 1998-10-07 EP disclosed
WO-1997022644-A1 COATING AGENT AND METHOD OF COATING, IN PARTICULAR FOR USE ON PLASTIC SUBSTRATES Herberts Gesellschaft mit beschränkter Haftung (DE) 1997-06-26 WO disclosed
EP-0513659-B1 Process for priming plastic substrates, coating to be used and its application HERBERTS & CO GMBH (DE) 1995-04-19 EP disclosed
US-5399383-A Process for priming plastic substrates, coating compositions for this purpose, and the use thereof HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-03-21 US disclosed
US-5297740-A Utilizing neutralized homo or copolymer of acrylic acid as dispersion aid in grinding calcium carbonate in water LANDSCHEIDT ALFONS (DE) 1994-03-29 US disclosed
US-5241011-A Neutralization ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 1993-08-31 US disclosed
EP-0260456-B1 PIGMENT DISPERSION AND ITS USE Herberts Gesellschaft mit beschränkter Haftung (DE) 1993-05-19 EP disclosed
EP-0513659-A1 Process for priming plastic substrates, coating to be used and its application Herberts Gesellschaft mit beschränkter Haftung (DE) 1992-11-19 EP disclosed
US-4980437-A OF LEATHER; COPOLYMER OF ACRYLIC ACID OR METHACRYLIC ACID AND N-ALKYL ACRLYLAMIDES OR METHACRYLAMIDES; IMPROVED ORGANOLEPTIC PROPERTIES, SMOOTHNESS, LUSTER CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1990-12-25 US disclosed
US-4813968-A Retanning process CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1989-03-21 US disclosed
EP-0260456-A2 Pigment dispersion and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-03-23 EP disclosed
EP-0260448-A2 Externally cross-linkable binder combination, aqueous coating compositions containing it and its use Herberts Gesellschaft mit beschränkter Haftung (DE) 1988-03-23 EP disclosed