Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CDC42 | P60953 | 1/20 | 0.45 |
| ▸ | RAC1 | P63000 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733706 | 0.90 | TBXA2R (0.50) | ALDH1A1TBXA2RGAACNR1CNR2 | |
| SCHEMBL8734674 | 0.88 | AKR1C3 (0.49) | ALDH1A1TBXA2RGAACNR1CNR2 | |
| SCHEMBL8731635 | 0.87 | TBXA2R (0.63) | ALDH1A1TBXA2RLMNAMEN1KMT2A | |
| SCHEMBL8730153 | 0.85 | TBXA2R (0.46) | ALDH1A1TBXA2RGAACNR1CNR2 | |
| SCHEMBL8733707 | 0.82 | TBXA2R (0.53) | ALDH1A1TBXA2RGAACNR1CNR2 | |
| SCHEMBL8730099 | 0.81 | TBXA2R (0.66) | TBXA2RTSHRMEN1KMT2A | |
| SCHEMBL8757138 | 0.79 | TBXA2R (0.62) | ALDH1A1TBXA2RTSHRMEN1KMT2A | |
| SCHEMBL8757815 | 0.78 | TBXA2R (0.54) | ALDH1A1TBXA2RGAACNR1CNR2 | |
| SCHEMBL8758402 | 0.78 | TBXA2R (0.63) | ALDH1A1TBXA2RLMNAPKMTSHR | |
| SCHEMBL8730079 | 0.76 | TBXA2R (0.61) | ALDH1A1TBXA2RPKMPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |