Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734682 | 0.90 | ALDH1A1 (0.50) | TBXA2RALDH1A1GAACNR1CNR2 | |
| SCHEMBL8734674 | 0.88 | AKR1C3 (0.49) | TBXA2RALDH1A1GAACNR1CNR2 | |
| SCHEMBL8730079 | 0.87 | TBXA2R (0.61) | TBXA2RALDH1A1PKMMEN1KMT2A | |
| SCHEMBL8730147 | 0.86 | TBXA2R (0.64) | TBXA2RMEN1KMT2A | |
| SCHEMBL8730153 | 0.85 | TBXA2R (0.46) | TBXA2RALDH1A1GAACNR1CNR2 | |
| SCHEMBL8733707 | 0.82 | TBXA2R (0.53) | TBXA2RALDH1A1GAACNR1CNR2 | |
| SCHEMBL8730099 | 0.81 | TBXA2R (0.66) | TBXA2RTSHRMEN1KMT2A | |
| SCHEMBL8757138 | 0.79 | TBXA2R (0.62) | TBXA2RALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8757815 | 0.78 | TBXA2R (0.54) | TBXA2RALDH1A1GAACNR1CNR2 | |
| SCHEMBL8758402 | 0.78 | TBXA2R (0.63) | TBXA2RALDH1A1PKMLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0773019-A1 | HYPERLIPEMIA REMEDY | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |