SCHEMBL8734752

SCHEMBL8734752

CC(C)OP(C)(=O)COS(=O)(=O)c1ccccc1SC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.33
FFAR1 O14842 1/20 0.33
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735018 0.90 FFAR4 (0.33) FFAR4FFAR1ALDH1A1L3MBTL1
SCHEMBL8735044 0.88 FFAR1 (0.32) FFAR4FFAR1ALDH1A1L3MBTL1
SCHEMBL8732452 0.87 FFAR1 (0.31) FFAR4FFAR1
SCHEMBL8732839 0.86 ALDH1A1 (0.33) ALDH1A1L3MBTL1
SCHEMBL8730058 0.85 TSHR (0.31) FFAR4FFAR1ALDH1A1
SCHEMBL8735757 0.85
SCHEMBL8732820 0.84 ALDH1A1 (0.32) ALDH1A1L3MBTL1
SCHEMBL8732229 0.82 MEN1 (0.38)
SCHEMBL8735050 0.82 LMNA (0.34) LMNA
SCHEMBL8729939 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed