⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187358 | 0.86 | CYP3A4 (0.30) | — | |
| SCHEMBL7192691 | 0.86 | CYP3A4 (0.36) | — | |
| SCHEMBL18489641 | 0.76 | CYP3A4 (0.38) | — | |
| SCHEMBL7155446 | 0.76 | CYP3A4 (0.31) | — | |
| SCHEMBL7155442 | 0.71 | — | — | |
| SCHEMBL28105393 | 0.69 | CYP3A4 (0.35) | — | |
| SCHEMBL28285647 | 0.69 | OPRM1 (0.34) | — | |
| SCHEMBL19245444 | 0.69 | DNM1 (0.42) | — | |
| SCHEMBL8080952 | 0.68 | — | — | |
| SCHEMBL6398645 | 0.68 | DNM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728769-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1998-08-19 | — | — | EP | disclosed |
| EP-0546573-A1 | Process for the preparation of stabilized polyolefins and products obtained therefrom | MONTELL NORTH AMERICA INC. (US) | 1993-06-16 | — | — | EP | disclosed |