SCHEMBL8734849

SCHEMBL8734849

CCc1cccc(SC(F)(F)F)c1S(=O)(=O)OC[PH](=O)O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 9/20 0.37
FFAR1 O14842 5/20 0.35
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
HSD11B1 P28845 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734846 0.86 FFAR4 (0.33) FFAR4FFAR1
SCHEMBL8854466 0.86 FFAR4 (0.36) FFAR4FFAR1GABRA1GABRB2HSD11B1
SCHEMBL8735017 0.85 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL8735547 0.85 FFAR4 (0.31) FFAR4
SCHEMBL8731808 0.85 LMNA (0.32) GABRA1GABRB2
SCHEMBL8729838 0.84 FFAR4 (0.32) FFAR4HSD11B1
SCHEMBL8732338 0.84 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL8854735 0.83 FFAR4 (0.34) FFAR4FFAR1
SCHEMBL8734613 0.81
SCHEMBL8729780 0.81 GABRA1 (0.38) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed