SCHEMBL8734897

SCHEMBL8734897

C[SiH2][Zr](c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.33
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3302834 0.98 SIGMAR1 (0.32) SIGMAR1HTR6HTR2A
SCHEMBL8731744 0.80 HTR6 (0.32) HTR6
Hydrochloric Acid SCHEMBL3304636 0.78 HTR6 (0.31) HTR6
SCHEMBL8755168 0.77 HTR2A (0.35) SIGMAR1HTR6HTR2A
SCHEMBL5276701 0.77 HTR2A (0.35) SIGMAR1HTR6HTR2A
Ethylene SCHEMBL819771 0.74 HTR6 (0.33) SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL5926290 0.73 SIGMAR1 (0.32) SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL5179760 0.72 HTR6 (0.33) SIGMAR1HTR6HTR2A
SCHEMBL7527698 0.72 HTR2A (0.36) SIGMAR1HTR6HTR2A
Hydrochloric Acid SCHEMBL5695978 0.72 HTR6 (0.33) SIGMAR1HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0615981-B1 Supported catalyst system, its preparation and its use in olefin polymerisation TARGOR GMBH (DE) 1998-05-06 EP claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed