Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172246 | 0.87 | NR4A2 (0.53) | NR4A2CREBBPMAPTALPLHTT | |
| SCHEMBL9846800 | 0.85 | NR4A2 (0.68) | NR4A2CREBBPMAPTALPLHTT | |
| SCHEMBL27505706 | 0.84 | PKM (0.57) | NR4A2CREBBPRAB9AMEN1KMT2A | |
| SCHEMBL1093530 | 0.82 | NR4A2 (1.00) | NR4A2CREBBPMAPTRAB9APBRM1 | |
| SCHEMBL30031033 | 0.82 | NR4A2 (1.00) | NR4A2CREBBPMAPTRAB9APBRM1 | |
| Hydrochloric Acid SCHEMBL28254334 | 0.81 | NR4A2 (0.97) | NR4A2CREBBPMAPTRAB9APBRM1 | |
| SCHEMBL30234471 | 0.81 | MAPT (0.53) | NR4A2MAPTCDK4CCND1PBRM1 | |
| SCHEMBL9272191 | 0.81 | MAPT (0.53) | NR4A2MAPTCDK4CCND1PBRM1 | |
| SCHEMBL20846298 | 0.80 | MAP2K1 (0.70) | NR4A2CREBBP | |
| SCHEMBL30610297 | 0.80 | MAP2K1 (0.70) | NR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1025786-C | Carbamoyl derivatives | ICI PLC (GB) | 1994-08-31 | — | — | CN | claimed |
| CN-1053604-A | CARBAMOYL DERIVATIVES | ICI PLC (GB) | 1991-08-07 | — | — | CN | claimed |
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |
| CN-1025786-C | Carbamoyl derivatives | ICI PLC (GB) | 1994-08-31 | — | — | CN | disclosed |
| CN-1053604-A | CARBAMOYL DERIVATIVES | ICI PLC (GB) | 1991-08-07 | — | — | CN | disclosed |
| CN-1030910-A | ALIPHATIC CARBOXAMIDEX | ICI AMERICA INC (US) | 1989-02-08 | — | — | CN | disclosed |