SCHEMBL8734987

SCHEMBL8734987

CCSc1cccc(C(F)(F)F)c1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.35
RXFP1 Q9HBX9 1/20 0.33
AR P10275 1/20 0.33
DDR1 Q08345 2/20 0.31
ACP3 P15309 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8729834 0.88 STK10 (0.33) CCR2ACP3
SCHEMBL8733162 0.86 AR (0.32) CCR2RXFP1AR
SCHEMBL8731835 0.84 KAT6A (0.34) RXFP1DDR1HPGD
SCHEMBL8732144 0.83 RXFP1 (0.31) CCR2RXFP1AR
SCHEMBL8735522 0.83 RXFP1 (0.31) CCR2RXFP1AR
SCHEMBL8735716 0.83 HPGD (0.32) HPGD
SCHEMBL8734830 0.83 HPGD (0.32) HPGD
SCHEMBL8734721 0.83 GABRA1 (0.38) ACP3HPGD
SCHEMBL8732888 0.82 AR (0.32) RXFP1AR
SCHEMBL8734622 0.81 SMN1; SMN2 (0.36) CCR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed