SCHEMBL8734830

SCHEMBL8734830

CCSc1cccc(CC)c1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PKM P14618 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734484 0.88 LMNA (0.32) ALDH1A1MAPTMMP2MMP9MMP12
SCHEMBL8735716 0.87 HPGD (0.32) HPGDALOX15HSD17B10ALDH1A1MAPT
SCHEMBL8731835 0.86 KAT6A (0.34) HPGDALOX15HSD17B10ALDH1A1MAPT
SCHEMBL8734622 0.86 SMN1; SMN2 (0.36) HPGDALOX15HSD17B10ALDH1A1MAPT
SCHEMBL8729944 0.85 ACHE (0.31) HPGD
SCHEMBL8732777 0.84 FFAR4 (0.37) GABRA1GABRB2
SCHEMBL8734987 0.83 CCR2 (0.35) HPGD
SCHEMBL8729899 0.83 HPGD (0.30) HPGD
SCHEMBL8735637 0.82
SCHEMBL8734828 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed