SCHEMBL8735003

SCHEMBL8735003

CCCc1cc(C(c2ccc(Oc3ccc(N4C(=O)C=CC4=O)cc3)c(CCC)c2)(C(F)(F)F)C(F)(F)F)ccc1Oc1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.43
NR1H2 P55055 14/20 0.42
NR1H3 Q13133 9/20 0.40
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
HTR2A P28223 1/20 0.37
SLC6A4 P31645 1/20 0.37
KCNH2 Q12809 1/20 0.37
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14891696 0.92 MGLL (0.43) MGLLNR1H2HTR2ASLC6A4KCNH2
SCHEMBL30806244 0.92 MGLL (0.43) MGLLNR1H2HTR2ASLC6A4KCNH2
SCHEMBL350368 0.87 MGLL (0.46) MGLLNR1H2NR1H3PPARGPPARD
SCHEMBL31314481 0.87 MGLL (0.46) MGLLNR1H2NR1H3PPARGPPARD
SCHEMBL8732314 0.85 NR1H2 (0.39) NR1H2NR1H3PPARGPPARDPPARA
SCHEMBL8729990 0.83 MGLL (0.46) MGLLFAAH
SCHEMBL8853344 0.81 MGLL (0.60) MGLLFAAH
SCHEMBL8732927 0.81 MGLL (0.46) MGLLFAAH
SCHEMBL194671 0.81 MGLL (0.43) MGLLNR1H2NR1H3PPARGPPARD
SCHEMBL30394499 0.81 MGLL (0.43) MGLLNR1H2NR1H3PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618269-B1 Thermosetting resin compositions and their use for making resin articles and thin film wiring boards HITACHI LTD (JP) 1998-11-11 EP disclosed
EP-0755979-A2 Thermosetting resin compositions and their use for thin film wiring boards HITACHI, LTD. (JP) 1997-01-29 EP disclosed
EP-0618269-A1 Thermosetting resin compositions and their use for thin film wiring boards HITACHI, LTD. (JP) 1994-10-05 EP disclosed