Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.58 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480847 | 0.76 | AVPR1A (0.66) | AVPR1AOXTRALDH1A1MAPTPKM | |
| SCHEMBL4879878 | 0.73 | AVPR1A (0.49) | AVPR1AOXTRALDH1A1MAPTPKM | |
| SCHEMBL3421771 | 0.70 | AVPR1A (0.67) | AVPR1AOXTRALDH1A1HTTHSD17B10 | |
| SCHEMBL17153832 | 0.70 | AVPR1A (0.49) | AVPR1AOXTRALDH1A1HTTHSD17B10 | |
| SCHEMBL6547461 | 0.70 | AVPR1A (0.45) | AVPR1AOXTRALDH1A1MAPTPKM | |
| SCHEMBL515383 | 0.70 | AVPR1A (0.92) | AVPR1AOXTRALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11586685 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTHSD17B10 | |
| SCHEMBL28320964 | 0.69 | AVPR1A (0.71) | AVPR1AOXTRALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL31711434 | 0.69 | AVPR1A (0.59) | AVPR1AOXTRALDH1A1MAPTPKM | |
| SCHEMBL29406171 | 0.68 | AVPR1A (0.89) | AVPR1AOXTRALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831911-A2 | SPIRONOLACTONE AND ANGIOTENSIN II ANTAGONIST COMBINATION THERAPY FOR TREATMENT OF CONGESTIVE HEART FAILURE | G.D. SEARLE & CO. (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0664802-A1 | N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1995-08-02 | — | — | EP | disclosed |