SCHEMBL8735236

SCHEMBL8735236

CCCP(=O)(O)CC.CO[SiH](OC)OC

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.45
GABBR1 Q9UBS5 2/20 0.45
GABRR1 P24046 1/20 0.34
LPAR3 Q9UBY5 6/20 0.33
LPAR2 Q9HBW0 3/20 0.33
PPARD Q03181 1/20 0.31
LPAR1 Q92633 2/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2487794 0.85
SCHEMBL8405561 0.83
SCHEMBL28110261 0.83
SCHEMBL9580952 0.79 GABBR2 (0.39) GABBR2GABBR1GABRR1LPAR3LPAR2
Propane SCHEMBL28733864 0.76 LPAR3 (0.41) LPAR3LPAR2FDPS
SCHEMBL2487051 0.74 GABBR2 (0.62) GABBR2GABBR1GABRR1LPAR3LPAR2
Phosphoric Acid SCHEMBL28961858 0.74 CA2 (0.38) FDPS
SCHEMBL497156 0.74
Phosphoric Acid SCHEMBL10420311 0.74 CA2 (0.38) FDPS
SCHEMBL20606620 0.73 GABBR2 (0.45) GABBR2GABBR1GABRR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552874-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1998-05-06 EP disclosed
EP-0552875-B1 Water repellents containing organosilicon compounds DOW CORNING (US) 1997-08-27 EP disclosed
EP-0552874-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
EP-0552875-A2 Water repellents containing organosilicon compounds DOW CORNING CORPORATION (US) 1993-07-28 EP disclosed
US-5205860-A Mixture of alkyltrioxysilane, coupling agents, and endcapped polysiloxane DOW CORNING CORPORATION (US) 1993-04-27 US disclosed