SCHEMBL873526

SCHEMBL873526

O=C(O)c1ccc(C(F)C(F)(F)C(F)(F)F)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.50
TDP1 Q9NUW8 5/20 0.50
MEN1 O00255 3/20 0.50
CYP2C9 P11712 3/20 0.50
KMT2A Q03164 3/20 0.50
CYP2C19 P33261 3/20 0.50
CYP2D6 P10635 1/20 0.50
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
DRD3 P35462 1/20 0.50
GRM4 Q14833 1/20 0.50
ALDH1A1 P00352 9/20 0.39
KDM4E B2RXH2 7/20 0.38
HPGD P15428 6/20 0.38
GRM1 Q13255 3/20 0.37
GRM2 Q14416 2/20 0.37
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833968 1.00 HSD17B10 (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
Water SCHEMBL8588310 0.98 HSD17B10 (0.49) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL28900515 0.98 HSD17B10 (0.49) HSD17B10TDP1MEN1CYP2C9KMT2A
Hydrochloric Acid SCHEMBL28444882 0.98 HSD17B10 (0.49) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL27770934 0.87 KMT2A (0.41) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL28070236 0.86 HSD17B10 (0.53) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL28376265 0.85 KEAP1 (0.49) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL28375830 0.85 KDM4E (0.53) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL4890614 0.84 POLB (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL4857668 0.82 FOLH1 (0.46) HSD17B10MEN1CYP2C9KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240212-A Material for forming polyimide by electrophoresis, insulating material and electrophoresis coating method 比亚迪股份有限公司 2024-06-25 CN claimed
CN-118221714-A Silicon-containing anhydride compound and preparation method thereof, polyimide compound and preparation method and application thereof 比亚迪股份有限公司 2024-06-21 CN claimed
WO-2024128683-A1 OPTICAL FILM HAVING EXCELLENT CRUSH RESISTANCE AND DISPLAY DEVICE COMPRISING SAME 코오롱인더스트리 주식회사 2024-06-20 WO claimed
CN-116423598-B Preparation method of wood core polyimide shell composite material 东北林业大学 2024-06-11 CN claimed
CN-118146713-A Polyimide electrophoretic paint, preparation method and application thereof 合肥汉之和新材料科技有限公司 2024-06-07 CN claimed
CN-117861451-A Cross-linked thermal rearranged polybenzoxazole hollow fiber gas separation membrane and preparation method and application thereof 北京化工大学 2024-04-12 CN claimed
CN-117069939-B Polyimide microsphere and preparation method thereof, negative electrode plate, battery and power utilization device 宁德时代新能源科技股份有限公司 2024-04-09 CN claimed
CN-117843632-A Diamine compound, polyimide acid, polyimide, preparation method and application thereof 比亚迪股份有限公司 2024-04-09 CN claimed
CN-117820270-A Synthesis method of hexafluorodianhydride 常州市阳光药业有限公司 2024-04-05 CN claimed
WO-2024071896-A1 OPTICAL FILM HAVING IMPROVED STIFFNESS AND DISPLAY DEVICE COMPRISING SAME 코오롱인더스트리 주식회사 2024-04-04 WO claimed
EP-0518060-A2 Polyimidesiloxane extended block copolymers OCCIDENTAL CHEMICAL CORPORATION (US) 1992-12-16 EP claimed
WO-1992017520-A1 PROCESS FOR THE PRODUCTION OF HIGH MOLECULAR WEIGHT POLYESTER RESINS M. & G. RICERCHE S.P.A. (IT) 1992-10-15 WO claimed
US-5025089-A Solvent suluble HOECHST CELANESE CORP. (US) 1991-06-18 US claimed
WO-1991005815-A1 PROCESS FOR THE CONTINUOUS PRODUCTION OF HIGH MOLECULAR WEIGHT POLYESTER RESIN PHOBOS N.V. (AN) 1991-05-02 WO claimed
EP-0422282-A1 Process for the continuous production of high molecular weight polyester resin PHOBOS N.V. (AN) 1991-04-17 EP claimed
EP-0299785-B1 WEAR RESISTANT SOLID FILM LUBRICANTS, THEIR PREPARATION AND USE ETHYL CORPORATION (US) 1991-02-13 EP claimed
US-4980447-A FILM FORMING HOECHST CELANESE CORP. (US) 1990-12-25 US claimed
US-4978737-A SUPERIOR ELECTRICAL AND MECHANICAL PROPERTIES HOECHST CELANESE CORP. (US) 1990-12-18 US claimed
EP-0354360-A1 Copolyimides derived from 2,2-bis (amino phenyl) hexafluoropropane HOECHST CELANESE CORPORATION (US) 1990-02-14 EP claimed
US-4045408-A Fluoro-anhydride curing agents and precursors thereof for fluorinated epoxy resins THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-08-30 US claimed