Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873526 | 1.00 | HSD17B10 (0.50) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| Water SCHEMBL8588310 | 0.98 | HSD17B10 (0.49) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL28900515 | 0.98 | HSD17B10 (0.49) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL28444882 | 0.98 | HSD17B10 (0.49) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL27770934 | 0.87 | KMT2A (0.41) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL28070236 | 0.86 | HSD17B10 (0.53) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL28376265 | 0.85 | KEAP1 (0.49) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL28375830 | 0.85 | KDM4E (0.53) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL4890614 | 0.84 | POLB (0.50) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL4857668 | 0.82 | FOLH1 (0.46) | HSD17B10MEN1CYP2C9KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408672-A4 | TOUGH, HIGH PERFORMANCE, ADDITION-TYPE THERMOPLASTIC POLYMERS | — | 1991-04-24 | — | — | EP | disclosed |
| EP-0408672-A1 | TOUGH, HIGH PERFORMANCE, ADDITION-TYPE THERMOPLASTIC POLYMERS | THE U.S. GOVERNMENT as represented by THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990003405-A1 | TOUGH, HIGH PERFORMANCE, ADDITION-TYPE THERMOPLASTIC POLYMERS | UNITED STATES GOVERNMENT, AS REPRESENTED BY THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1990-04-05 | — | — | WO | disclosed |