SCHEMBL8735266

SCHEMBL8735266

CCCNC(=O)c1c(Cl)cccc1NC1(C)CCCC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 11/20 0.44
POLB P06746 2/20 0.42
P2RX7 Q99572 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
HTT P42858 1/20 0.40
HPGD P15428 2/20 0.39
THRB P10828 1/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KMT2A Q03164 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735092 0.85 CCR6 (0.40) SLC6A9POLBP2RX7L3MBTL1HPGD
SCHEMBL8735202 0.83 HPGD (0.61) POLBP2RX7L3MBTL1HPGDALDH1A1
SCHEMBL8730842 0.82 HPGD (0.60) SLC6A9POLBL3MBTL1HPGDALDH1A1
SCHEMBL8734965 0.79 CCR6 (0.41) POLBALDH1A1
SCHEMBL10289215 0.78 ALDH1A1 (0.57) SLC6A9POLBP2RX7L3MBTL1HTT
SCHEMBL8733042 0.76 SLC6A9 (0.45) SLC6A9POLBP2RX7L3MBTL1HPGD
SCHEMBL8730894 0.76 HTT (0.44) POLBP2RX7L3MBTL1HTTHPGD
SCHEMBL8730858 0.74 HTT (0.43) POLBP2RX7L3MBTL1HTTHPGD
SCHEMBL8732675 0.74 POLB (0.43) POLBP2RX7L3MBTL1HTTHPGD
SCHEMBL8733063 0.73 POLB (0.42) POLBP2RX7L3MBTL1HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749416-B1 SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS MONSANTO CO (US) 1998-12-23 EP disclosed