Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.48 |
| ▸ | ANPEP | P15144 | 4/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.48 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064384 | 0.79 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL21012314 | 0.77 | LAP3 (0.62) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| Hydrochloric Acid SCHEMBL20474466 | 0.76 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| Hydrochloric Acid SCHEMBL17595990 | 0.76 | LAP3 (0.60) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL4814562 | 0.76 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL12234221 | 0.74 | ALPI (0.58) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL22369889 | 0.74 | ALPI (0.58) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL7547746 | 0.74 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL6430008 | 0.74 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL15314130 | 0.72 | CYP3A4 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708004-A | ENZYME INHIBITORS FOR TREATMENT OF AIDS | MONSANTO COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5703076-A | TREATING HIV, AIDS | G. D. SEARLE & CO. (US) | 1997-12-30 | — | — | US | disclosed |
| US-5510349-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510487-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5510378-A | Retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |