Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430008 | 1.00 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEPNPC1 | |
| SCHEMBL6225271 | 0.86 | LAP3 (0.51) | LAP3ANPEPRNPEPDNPEPNPC1 | |
| SCHEMBL7360300 | 0.82 | BACE1 (0.40) | LAP3ANPEPRNPEPDNPEPREN | |
| SCHEMBL9064384 | 0.82 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCTRB1 | |
| SCHEMBL8840299 | 0.81 | BACE1 (0.40) | NPC1RAB9AMAPTRENLMNA | |
| SCHEMBL6448962 | 0.80 | NPC1 (0.51) | NPC1RAB9AMAPTCTRB1LMNA | |
| SCHEMBL9742824 | 0.80 | NPC1 (0.51) | NPC1RAB9AMAPTCTRB1LMNA | |
| SCHEMBL7358895 | 0.78 | REN (0.38) | LAP3ANPEPRNPEPDNPEPREN | |
| SCHEMBL7358901 | 0.76 | CYP3A4 (0.41) | RENLMNA | |
| SCHEMBL7360719 | 0.76 | BACE1 (0.36) | NPC1RAB9AMAPTREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750648-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1995006061-A1 | RETROVIRAL PROTEASE INHIBITORS AND COMBINATIONS THEREOF | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |