Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706024 | 0.85 | ESR2 (0.57) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10791207 | 0.83 | ESR1 (0.55) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7906825 | 0.82 | ESR1 (0.53) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL12002346 | 0.80 | ESR1 (0.52) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL491176 | 0.79 | ESR1 (0.50) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5682331 | 0.77 | CNR2 (0.52) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9618804 | 0.77 | ADRB2 (0.50) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL21077907 | 0.76 | ESR1 (0.47) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL4564526 | 0.76 | CNR2 (0.58) | ESR1ESR2SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL12000487 | 0.76 | ESR1 (0.47) | ESR1ESR2SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374887-B1 | Thermoplastic resin composition | KANEGAFUCHI CHEMICAL IND (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5017651-A | Polyester, polyamide, synthetic rubber | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0374887-A2 | Thermoplastic resin composition | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0068014-B2 | BENZOATE ESTER TERMINATED POLYESTER-CARBONATE | GENERAL ELECTRIC COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |