Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734945 | 0.79 | MAPT (0.34) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6058559 | 0.73 | KDM1A (0.41) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL27659701 | 0.69 | ALDH1A1 (0.33) | LMNAMAPK1MEN1KMT2ACA2 | |
| SCHEMBL8736634 | 0.64 | KDM1A (0.36) | — | |
| SCHEMBL8737332 | 0.63 | KDM1A (0.33) | MAPTLMNAMEN1GAAKMT2A | |
| SCHEMBL12054818 | 0.55 | KDM1A (0.47) | — | |
| Bromobenzene SCHEMBL22041640 | 0.55 | ALDH1A1 (0.65) | MAPTLMNAMAPK1MEN1NPC1 | |
| Bromobenzene SCHEMBL27288927 | 0.55 | ALDH1A1 (0.65) | MAPTLMNACYP1A2MAPK1MEN1 | |
| Hydroxyamine SCHEMBL1506235 | 0.55 | MEN1 (0.46) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL23393891 | 0.54 | CHRNA7 (0.44) | LMNAMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | disclosed |