Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058559 | 0.83 | KDM1A (0.41) | KDM1AALDH1A1MAPTLMNA | |
| SCHEMBL5608796 | 0.73 | KDM1A (0.33) | KDM1A | |
| SCHEMBL5608315 | 0.69 | KDM1A (0.30) | KDM1A | |
| SCHEMBL8735355 | 0.63 | MAPT (0.34) | MAPTMEN1GAAHPGDKMT2A | |
| SCHEMBL8735310 | 0.59 | KDM1A (0.33) | KDM1A | |
| SCHEMBL7398947 | 0.57 | KDM1A (0.39) | KDM1AALDH1A1 | |
| Nitrobenzene SCHEMBL28164256 | 0.55 | ALDH1A1 (0.76) | ALDH1A1TDP1MEN1HPGDKMT2A | |
| SCHEMBL9489237 | 0.55 | KDM1A (0.44) | KDM1AALDH1A1MAPTTDP1GAA | |
| Nitrobenzene SCHEMBL8667167 | 0.55 | ALDH1A1 (0.59) | ALDH1A1TDP1MEN1HPGDKMT2A | |
| Nitrobenzene SCHEMBL250669 | 0.54 | ALDH1A1 (0.67) | ALDH1A1TDP1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | claimed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | claimed |
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | disclosed |