SCHEMBL8735382

SCHEMBL8735382

CC[Si](OC)(OC)c1ccccc1.CO[Si](OC)(OC)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
TP53 P04637 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296205 0.92 CA4 (0.35) POLBTP53CA4
SCHEMBL37986 0.82 CA4 (0.41) POLBCA4
Alcohol SCHEMBL4340926 0.81 ESR1 (0.35) POLBTP53CA4
Water SCHEMBL18606224 0.80 POLB (0.39) POLBCA4
Ammonia Solution, Strong SCHEMBL2330946 0.80 POLB (0.39) POLBCA4
SCHEMBL1974068 0.80 CA1 (0.41) POLBTP53CA4
SCHEMBL704447 0.80 ESR1 (0.37)
SCHEMBL3295855 0.80 TSHR (0.32) TP53CA4
SCHEMBL19817027 0.78 CA4 (0.38) CA4
Methylamine SCHEMBL28410618 0.78 POLB (0.38) POLBCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0159150-B2 Supported titanium-containing olefin polymerisation catalyst component and process for its production AMOCO CORP (US) 1998-04-08 EP disclosed
EP-0159150-B1 MAGNESIUM HYDROCARBYL CARBONATE SUPPORTS AMOCO CORPORATION (US) 1989-09-13 EP disclosed
EP-0171179-B1 MAGNESIUM CARBOXYLATE SUPPORTS AMOCO CORPORATION (US) 1989-03-08 EP disclosed
US-4612299-A Magnesium carboxylate supports AMOCO CORPORATION (US) 1986-09-16 US disclosed
EP-0171179-A1 Magnesium carboxylate supports AMOCO CORPORATION (US) 1986-02-12 EP disclosed
US-4540679-A TRANSITION METAL COMPONENT, CATALYST AMOCO CORPORATION (US) 1985-09-10 US disclosed