SCHEMBL8735383

SCHEMBL8735383

CCOC(=O)C(=O)Cc1ccccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TSHR P16473 1/20 0.43
ALDH1A1 P00352 3/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PKM P14618 1/20 0.41
HSPA5 P11021 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637044 0.84 CTDSP1 (0.50) CTDSP1MEN1KMT2AMAPTGAA
SCHEMBL27953552 0.83 AKR1B1 (0.50) AKR1B1CA12CA1CA2CA7
SCHEMBL29592621 0.82 PKM (0.58) AKR1B1CA12CA1CA2CA7
SCHEMBL1009146 0.82 PKM (0.58) AKR1B1CA12CA1CA2CA7
SCHEMBL7642355 0.81 ALDH1A1 (0.50) CTDSP1MEN1KMT2AMAPTGAA
SCHEMBL5964018 0.81 CTDSP1 (0.48) CTDSP1CA12CA1CA2CA9
SCHEMBL5804843 0.81 CTDSP1 (0.51) CTDSP1MEN1KMT2AMAPTGAA
SCHEMBL7636047 0.81 CTDSP1 (0.48) CTDSP1MEN1KMT2AMAPTGAA
SCHEMBL1679778 0.81 ALDH1A1 (0.51) CTDSP1MEN1KMT2AMAPTGAA
SCHEMBL7634089 0.80 KMT2A (0.54) CTDSP1MEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1083422-C Process for production of phenyllatic acid derivative MITSUBISHI ARTIFICIAL SILK CO (JP) 2002-04-24 CN disclosed
EP-0696566-B1 Process for production of phenyllactic acid derivative NITTO CHEMICAL INDUSTRY CO LTD (JP) 1998-06-10 EP disclosed
US-5684186-A HYDROGENATION OF A PHENYLPYRUVIC DERIVATIVE NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-11-04 US disclosed
CN-1122325-A Process for production of phenyllatic acid derivative NITTO CHEMICAL INDUSTRY CO LTD (JP) 1996-05-15 CN disclosed
EP-0696566-A1 Process for production of phenyllactic acid derivative NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1996-02-14 EP disclosed