Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093382 | 0.82 | ALDH1A1 (0.41) | LMNACA2HSD17B10HPGDCYP1A2 | |
| SCHEMBL6630329 | 0.80 | ALDH1A1 (0.42) | LMNACA2HSD17B10HPGDCYP1A2 | |
| SCHEMBL483064 | 0.76 | SMN1; SMN2 (0.37) | LMNAMPLTDP1KDM4EALDH1A1 | |
| SCHEMBL17707249 | 0.75 | SNCA (0.36) | LMNACA2HSD17B10HIF1ACYP1A2 | |
| SCHEMBL852203 | 0.74 | ALDH1A1 (0.44) | LMNACA2HSD17B10HPGDHIF1A | |
| SCHEMBL1713483 | 0.71 | ALDH1A1 (0.45) | LMNACA2HSD17B10HPGDHIF1A | |
| SCHEMBL4285482 | 0.70 | CYP1A2 (0.41) | HSD17B10HPGDHIF1ACYP1A2ESR1 | |
| SCHEMBL8816822 | 0.68 | — | — | |
| SCHEMBL8816827 | 0.68 | — | — | |
| Sulfuric Acid SCHEMBL9324873 | 0.67 | CYP1A2 (0.59) | LMNACA2HSD17B10HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |