SCHEMBL483064

SCHEMBL483064

O=S(=O)(O)c1[c]c2ccccc2cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
TSHR P16473 1/20 0.37
CTRB1 P17538 1/20 0.34
SNCA P37840 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
LMNA P02545 2/20 0.31
MPL P40238 1/20 0.30
CTRC Q99895 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP2D6 P10635 1/20 0.30
TTR P02766 1/20 0.30
FABP4 P15090 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17707249 0.83 SNCA (0.36) SMN1; SMN2TSHRSNCAL3MBTL1LMNA
SCHEMBL11337721 0.82 CA1 (0.32) SMN1; SMN2L3MBTL1LMNAHTTTDP1
SCHEMBL11650093 0.80 HPRT1 (0.42) TSHRCTRB1MPLCTRCALDH1A1
SCHEMBL3323118 0.80 KEAP1 (0.35) L3MBTL1LMNA
SCHEMBL9400244 0.80 LMNA (0.42) LMNA
SCHEMBL6630329 0.77 ALDH1A1 (0.42) SMN1; SMN2TSHRSNCALMNAKDM4E
SCHEMBL8816827 0.76
SCHEMBL1713483 0.76 ALDH1A1 (0.45) SMN1; SMN2TSHRSNCALMNAKDM4E
SCHEMBL29093382 0.76 ALDH1A1 (0.41) SMN1; SMN2TSHRSNCALMNAKDM4E
SCHEMBL8735604 0.76 LMNA (0.36) TSHRLMNAMPLKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 656 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103012259-B Isosorbide-5-Nitrae-disubstituted 3-cyano-pyridone derivatives and the purposes as MGLUR2 receptor positive allosteric modulators thereof ORTHO MCNEIL JANSSEN PHARM (US) 2015-10-28 CN claimed
CN-101952285-A Amino triazoles as PI3K inhibitors CELLZOME LTD 2011-01-19 CN claimed
US-7588878-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-09-15 US claimed
US-7553603-B2 Inkless printing paper and method XEROX CORPORATION (US) 2009-06-30 US claimed
US-20080311518-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
US-20080311517-A1 INKLESS PRINTING PAPER AND METHOD XEROX CORPORATION (US) 2008-12-18 US claimed
EP-2003503-A1 Inkless printing paper and method Xerox Corporation (US) 2008-12-17 EP claimed
CN-100424082-C 4- (piperidinyl-pyrrolidinyl-alkyl-ureido) -quinolines as urotensin II receptor antagonists ACTELION PHARMACEUTICALS LTD (CH) 2008-10-08 CN claimed
EP-1124905-B1 POLYMER COATED CARBON PRODUCTS AND OTHER PIGMENTS AND METHODS OF MAKING SAME BY AQUEOUS MEDIA POLYMERIZATIONS OR SOLVENT COATING METHODS CABOT CORP (US) 2006-06-21 EP claimed
EP-0799281-B2 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2006-03-29 EP claimed
EP-0027950-B1 FIBRE-REACTIVE CHROMIUM COMPLEX DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1984-02-15 EP claimed
US-4416815-A Fiber-reactive unsymmetrical 1:2 chromium complex azo dyes CIBA-GEIGY CORPORATION (US) 1983-11-22 US claimed
EP-0043560-B1 WATER-SOLUBLE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-16 EP claimed
EP-0017841-A1 Polyazo dyestuffs and their use in dyeing fibrous materials containing nitrogen BAYER AG (DE) 1980-10-29 EP claimed
US-4158094-A BLOWING AGENTS GENERAL ELECTRIC COMPANY (US) 1979-06-12 US claimed
US-4108887-A Divinyl stilbenes as optical brighteners SANDOZ LTD. (CH) 1978-08-22 US claimed
US-4097476-A ANIONIC SUBSTRATES SANDOZ LTD. (CH) 1978-06-27 US claimed
US-4079051-A 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs CIBA-GEIGY CORPORATION (US) 1978-03-14 US claimed
US-4033944-A Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs CIBA-GEIGY CORPORATION (US) 1977-07-05 US claimed
US-4010150-A Red copper complexes of disazo compounds containing triazine groups NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-03-01 US claimed