Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732748 | 0.91 | CYSLTR1 (0.62) | CYSLTR1CYP19A1 | |
| SCHEMBL8732426 | 0.90 | CYSLTR1 (0.61) | CYSLTR1ALDH1A1 | |
| SCHEMBL8736498 | 0.90 | CYSLTR1 (0.63) | CYSLTR1CYP19A1 | |
| SCHEMBL8733757 | 0.88 | CYSLTR1 (0.72) | CYSLTR1 | |
| SCHEMBL8734190 | 0.85 | CYSLTR1 (0.81) | CYSLTR1ALOX5 | |
| SCHEMBL8735635 | 0.85 | CYSLTR1 (0.68) | CYSLTR1ALOX5 | |
| SCHEMBL7808132 | 0.81 | ALOX5 (0.63) | CYSLTR1ALOX5 | |
| SCHEMBL8736040 | 0.80 | CYSLTR1 (0.60) | CYSLTR1 | |
| SCHEMBL8800199 | 0.80 | ALOX5 (0.72) | CYSLTR1ALOX5 | |
| SCHEMBL8736452 | 0.79 | CYSLTR1 (0.74) | CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | disclosed |