SCHEMBL8735660

SCHEMBL8735660

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)cc(-c4nc(-c5ccccc5)cc(-c5ccccc5)n4)c3)cc21

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.34
▸ ATM Q13315 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MEN1 O00255 6/20 0.33
▸ KMT2A Q03164 6/20 0.33
▸ ALDH1A1 P00352 6/20 0.33
▸ MAPT P10636 5/20 0.33
▸ HPGD P15428 5/20 0.33
▸ NTSR1 P30989 1/20 0.33
▸ PDE10A Q9Y233 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ GLA P06280 1/20 0.32
▸ PDK2 Q15119 6/20 0.32
▸ FLT3 P36888 2/20 0.31
▸ RXFP1 Q9HBX9 2/20 0.31
▸ ACACA Q13085 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736965 0.97 MEN1 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8736116 0.96 KDM4E (0.36) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8735461 0.96 MEN1 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8735314 0.95 MEN1 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8735667 0.95 PDK2 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8736975 0.95 PDK2 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8734563 0.95 MEN1 (0.33) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8736944 0.95 MEN1 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8735664 0.95 MEN1 (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL8734511 0.95 MEN1 (0.35) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-9266851-B2 Fluorene-containing aromatic compound, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-23 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO. LTD. (JP) 2012-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126217-A1 FLUORENE-CONTAINING AROMATIC COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NR0B2, AFF2, AFF1 KDM4E 2744/4885ATM 4148/4885L3MBTL1 3195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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