SCHEMBL8735688

SCHEMBL8735688

CCSc1cccc(Cl)c1S(=O)(=O)OCP(=O)(OC(C)C)OC(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732408 0.94 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL8732786 0.93 MEN1 (0.32) TSHRSMN1; SMN2
SCHEMBL8734751 0.90 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL8729940 0.90 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL8734607 0.87 HPGD (0.30)
SCHEMBL8729899 0.87 HPGD (0.30)
SCHEMBL8734923 0.86 SMN1; SMN2 (0.38) TSHRSMN1; SMN2
SCHEMBL8735690 0.86
SCHEMBL8735611 0.86 HSD17B10 (0.33)
SCHEMBL8730160 0.84 HSD11B1 (0.33) TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed