SCHEMBL8735611

SCHEMBL8735611

CCOP(=O)(COS(=O)(=O)c1c(Cl)cccc1SCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732786 0.91 MEN1 (0.32) HSD17B10MEN1KMT2A
SCHEMBL8732012 0.87 HSD17B10 (0.35) HSD17B10MEN1KMT2A
SCHEMBL8729944 0.86 ACHE (0.31) ACHE
SCHEMBL8731896 0.86 ACHE (0.31) ACHE
SCHEMBL8735688 0.86 TSHR (0.34)
SCHEMBL8734629 0.85 KAT6A (0.33) ACHE
SCHEMBL8734622 0.85 SMN1; SMN2 (0.36) HSD17B10
SCHEMBL8732408 0.83 TSHR (0.31)
SCHEMBL8733162 0.82 AR (0.32)
SCHEMBL8734627 0.82 SLC40A1 (0.33) HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed