Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003567 | 0.87 | HDAC3 (0.33) | NOS2 | |
| SCHEMBL8730390 | 0.83 | NR1I2 (0.47) | NOS2NR1I2HTTNPSR1CNR2 | |
| SCHEMBL3294064 | 0.81 | PLAT (0.46) | PLAT | |
| SCHEMBL22096777 | 0.81 | NR1I2 (0.37) | NR1I2 | |
| SCHEMBL28755439 | 0.80 | LMNA (0.45) | NR1I2HTTCNR2 | |
| SCHEMBL29073856 | 0.80 | NR1I2 (0.39) | NOS2NR1I2HTTCNR2 | |
| SCHEMBL3289894 | 0.79 | HRH3 (0.45) | NR1I2HRH3ESR1ESR2HTT | |
| SCHEMBL29531580 | 0.78 | LMNA (0.43) | NR1I2HTTCNR2 | |
| Potassium SCHEMBL29530864 | 0.78 | LMNA (0.43) | NR1I2HTTCNR2 | |
| SCHEMBL7834476 | 0.78 | OPRM1 (0.34) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706987-B1 | Process for preparing alkylated aromatic carboxylic acids and carboxylic acid halogenides | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| US-5616787-A | REACTING THE CORRESPONDING AROMATIC HYDROCARBON WITH CARBON DIOXIDE | CIBA-GEIGY CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0706987-A1 | Process for preparing alkylated aromatic carboxylic acids and carboxylic acids halogenides | CIBA-GEIGY AG (CH) | 1996-04-17 | — | — | EP | disclosed |