Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 5/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2023894 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9387332 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9773803 | 0.81 | GSK3B (0.44) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8735858 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10901383 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL12638001 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL3400695 | 0.77 | TOP2A (0.61) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL12831519 | 0.77 | PIM1 (0.40) | KDM4EALDH1A1HPGDHSD17B10TOP2A | |
| SCHEMBL10669670 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL8129957 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1POLBTOP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470578-B1 | Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KK (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5399553-A | Oral absorbability | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-03-21 | — | — | US | disclosed |
| US-5254685-A | Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0470578-A1 | Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |