SCHEMBL8735932

SCHEMBL8735932

CCOC(COC)O[Si](OC(COC)OCC)(OC(COC)OCC)OC(COC)OCC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2332578 0.82 THRB (0.42) THRBLMNA
SCHEMBL8672454 0.77 THRB (0.38) THRBLMNA
SCHEMBL5694826 0.77
SCHEMBL27617519 0.73
SCHEMBL28547222 0.73 THRB (0.35) THRBLMNA
SCHEMBL646299 0.73 MEN1 (0.31)
Ether SCHEMBL4309950 0.71 THRB (0.33) THRBLMNA
SCHEMBL8158638 0.71 THRB (0.33) THRBLMNA
SCHEMBL8652064 0.70 THRB (0.32) THRBLMNA
SCHEMBL28482501 0.68 ADRB2 (0.32) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592575-B1 ORGANIC-INORGANIC POLYMERIC COMPOSITES DU PONT (US) 1998-03-18 EP disclosed
US-5252654-A Interpenetrating polymer network; protective coating, optics E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-10-12 US disclosed