SCHEMBL8735938

SCHEMBL8735938

Cc1cc(-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc(-n2c3ccccc3c3ccncc32)c1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.37
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
DYRK1A Q13627 2/20 0.35
CYP11B2 P19099 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MDM2 Q00987 1/20 0.35
MAPK14 Q16539 2/20 0.34
TOP2A P11388 1/20 0.34
ALOX5 P09917 1/20 0.34
KMT2A Q03164 1/20 0.33
CDK4 P11802 1/20 0.33
CDK6 Q00534 1/20 0.33
GSK3B P49841 1/20 0.33
KCNH2 Q12809 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12442620 0.92 ATM (0.33) ATMKDM4EL3MBTL1DYRK1ACYP11B2
SCHEMBL7602363 0.88 L3MBTL1 (0.47) ATMKDM4EL3MBTL1ALDH1A1KMT2A
SCHEMBL14595446 0.86 KDM4E (0.43) ATMKDM4EL3MBTL1DYRK1ACYP11B2
SCHEMBL6113766 0.83 MAOA (0.44) ATMKDM4EL3MBTL1DYRK1AALDH1A1
SCHEMBL16547043 0.79 KDM4E (0.42) ATMKDM4EL3MBTL1ALDH1A1MAPK14
SCHEMBL1102616 0.79 MAPT (0.39) ATMKDM4EALDH1A1TOP2AALOX5
SCHEMBL11978684 0.79 KDM4E (0.48) ATMKDM4EL3MBTL1ALDH1A1MDM2
SCHEMBL4546816 0.78 L3MBTL1 (0.52) ATMKDM4EL3MBTL1ALDH1A1KMT2A
SCHEMBL29351241 0.78 L3MBTL1 (0.52) ATMKDM4EL3MBTL1ALDH1A1KMT2A
SCHEMBL8735564 0.78 KDM4E (0.33) ATMKDM4EL3MBTL1DYRK1ACYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755152-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-05 US disclosed
US-9755152-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-05 US disclosed
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-06-04 US disclosed
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-06-04 US disclosed
US-8927119-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-01-06 US disclosed
US-8927119-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-01-06 US disclosed
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-05-24 US disclosed
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 ATM 2631/4885KDM4E 1576/4885L3MBTL1 3679/4885
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 ATM 2631/4885KDM4E 1576/4885L3MBTL1 3679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.