Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | FUT4 | P22083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39598 | 0.79 | SELL (0.42) | THRBALDH1A1MAPTTDP1HMGB1 | |
| SCHEMBL5152690 | 0.77 | MCL1 (0.42) | MCL1TP53 | |
| SCHEMBL10782332 | 0.76 | HSD17B10 (0.40) | THRBPTGS2ALDH1A1MAPTTDP1 | |
| SCHEMBL11121112 | 0.73 | HSD17B10 (0.43) | THRBALDH1A1MAPTTDP1HMGB1 | |
| SCHEMBL31324071 | 0.73 | HSD17B10 (0.43) | THRBALDH1A1MAPTTDP1HMGB1 | |
| SCHEMBL27847670 | 0.71 | KDM4E (0.42) | THRBPTGS2ALDH1A1MAPTTDP1 | |
| SCHEMBL7737317 | 0.71 | PTPN1 (0.40) | THRBALDH1A1TDP1HMGB1CXCL12 | |
| SCHEMBL3787270 | 0.70 | PTPN1 (0.40) | THRBPTGS2ALDH1A1TDP1MCL1 | |
| SCHEMBL15668658 | 0.70 | AKR1C2 (0.44) | THRBMCL1SMN1; SMN2 | |
| SCHEMBL28382103 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850987-A1 | Improved PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-07-01 | — | — | EP | disclosed |