Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735952 | 0.77 | THRB (0.34) | MCL1TP53 | |
| SCHEMBL5586611 | 0.76 | ESR1 (0.35) | MCL1ESR1RARBTP53PPARA | |
| SCHEMBL5590538 | 0.73 | THRA (0.36) | ESR1RARBTP53 | |
| SCHEMBL28698678 | 0.73 | KAT8 (0.48) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL39598 | 0.72 | SELL (0.42) | MCL1TP53 | |
| SCHEMBL5590756 | 0.72 | PLA2G2A (0.34) | MCL1ESR1RARBTP53AKR1C4 | |
| SCHEMBL7088092 | 0.72 | TSHR (0.49) | TP53 | |
| SCHEMBL5589124 | 0.71 | PLA2G2A (0.36) | MCL1ESR1RARBTP53AKR1C4 | |
| SCHEMBL5590091 | 0.71 | PLA2G2A (0.36) | MCL1ESR1RARBTP53AKR1C4 | |
| SCHEMBL5588273 | 0.71 | PLA2G2A (0.36) | MCL1ESR1RARBTP53AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245403-B1 | Thermographic recording material with improved image tone. | AGFA GEVAERT (BE) | 2007-01-03 | — | — | EP | disclosed |
| US-6774084-B2 | BLACK AND WHITE LIGHT-INSENSITIVE THERMOGRAPHIC RECORDING MEDIA COMPRISING A THERMOSENSITIVE ELEMENT HAVING ORGANIC SILVER SALT, A 1,2-DIHYDROXYBENZENE CONTAINING AN ESTER OR SULFOXIDE GROUP AND BINDER; COVERING POWER; STORAGE STABILITY | AGFA-GEVAERT (BE) | 2004-08-10 | — | — | US | disclosed |
| US-20030064891-A1 | Thermographic recording material with improved image tone | AGFA-GEVAERT (BE) | 2003-04-03 | — | — | US | disclosed |
| EP-1245403-A1 | Thermographic recording material with improved image tone. | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | disclosed |