Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849371 | 0.82 | CHRM2 (0.69) | CHRM2CYP1A2CYP2D6ALDH1A1TDP1 | |
| SCHEMBL12831689 | 0.80 | RAB9A (0.48) | CHRM2ALDH1A1TDP1RAB9ANPC1 | |
| SCHEMBL1532367 | 0.76 | — | — | |
| SCHEMBL2003566 | 0.76 | CHRM2 (0.52) | CHRM2CYP1A2CYP2D6ALDH1A1TDP1 | |
| SCHEMBL9483777 | 0.76 | MAPT (0.58) | CHRM2CYP1A2CYP2D6TDP1L3MBTL1 | |
| SCHEMBL18756794 | 0.76 | ALDH1A1 (0.53) | CHRM2CYP1A2CYP2D6ALDH1A1TDP1 | |
| SCHEMBL1488104 | 0.75 | — | — | |
| SCHEMBL1025241 | 0.75 | — | — | |
| SCHEMBL8146532 | 0.75 | ALDH1A1 (0.54) | CHRM2CYP1A2CYP2D6ALDH1A1TDP1 | |
| Ammonia Solution, Strong SCHEMBL9755558 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200061072-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2020-02-27 | — | — | US | disclosed |
| US-10220040-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2019-03-05 | — | — | US | disclosed |
| US-20180064718-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | ABIONYX PHARMA (FR) | 2018-03-08 | — | — | US | disclosed |
| US-20180064718-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | ABIONYX PHARMA (FR) | 2018-03-08 | — | — | US | disclosed |
| US-9757381-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-09-12 | — | — | US | disclosed |
| US-9757381-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-09-12 | — | — | US | disclosed |
| EP-2629776-B1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-08-16 | — | — | EP | disclosed |
| US-9713619-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-25 | — | — | US | disclosed |
| US-9713619-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2017-07-25 | — | — | US | disclosed |
| US-20160361318-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2016-12-15 | — | — | US | disclosed |
| US-20150344455-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2015-12-03 | — | — | US | disclosed |
| US-20150344455-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2015-12-03 | — | — | US | disclosed |
| US-9085585-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2015-07-21 | — | — | US | disclosed |
| US-9085585-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CERENIS THERAPEUTICS HOLDING SA (FR) | 2015-07-21 | — | — | US | disclosed |
| US-20130267554-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2013-10-10 | — | — | US | disclosed |
| US-20130267554-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CERENIS THERAPEUTICS HOLDING SA (FR) | 2013-10-10 | — | — | US | disclosed |
| US-8349833-B2 | Compounds, compositions and methods useful for cholesterol mobilisation | CERENIS THERAPEUTICS HOLDING SA (FR) | 2013-01-08 | — | — | US | disclosed |
| US-8349833-B2 | Compounds, compositions and methods useful for cholesterol mobilisation | CERENIS THERAPEUTICS HOLDING SA (FR) | 2013-01-08 | — | — | US | disclosed |
| US-20120129856-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | CERENIS THERAPEUTICS SA (FR) | 2012-05-24 | — | — | US | disclosed |
| US-20120129856-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | CERENIS THERAPEUTICS SA (FR) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064718-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
| US-10220040-B2 | Compounds, compositions and methods useful for cholesterol mobilization | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
| US-20120129856-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION | CETP, NPC1L1, NPC1 | CHRM2 1192/4885CYP1A2 646/4885CYP2D6 628/4885 |
| US-20150344455-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
| US-20130267554-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
| US-20200061072-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
| US-20160361318-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | CHRM2 732/4885CYP1A2 1769/4885CYP2D6 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.