Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | RARG | P13631 | 6/20 | 0.43 |
| ▸ | RARA | P10276 | 5/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154631 | 0.85 | RXRA (0.70) | RXRARXRBCYP26B1CYP26A1CYP3A4 | |
| SCHEMBL9702383 | 0.81 | RARB (0.69) | RXRARXRBCYP26B1CYP26A1CYP3A4 | |
| SCHEMBL6144008 | 0.81 | RXRA (0.47) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL6144003 | 0.81 | RXRA (0.47) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL6148846 | 0.80 | RXRA (0.46) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL6148854 | 0.80 | RXRA (0.46) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL6147966 | 0.80 | PPARG (0.53) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL6147959 | 0.80 | PPARG (0.53) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL10453144 | 0.79 | PDE4A (0.34) | RXRARXRBPPARGCYP26B1CYP26A1 | |
| SCHEMBL7759792 | 0.79 | RXRA (0.70) | RXRARXRBCYP26B1CYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849729-A | Use of hydrolyzed cocoa butter for percutaneous absorption | HERSHEY FOODS CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| US-5468495-A | Methods of preventing and reducing the size of Striae distensae lesions | KLIGMAN ALBERT M (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0415458-A2 | Use of retinoids for preventing and reducing the size of striae distensae lesions | Kligman, Albert M. (US) | 1991-03-06 | — | — | EP | disclosed |